inquiry@rdetect.com 【Product Details】
Morphine is the most important alkaloid in opium (content about 10-15%), which was first isolated from opium by French chemist F. Zeltina in 1806.
Pure morphine is colourless or white crystal or powder, insoluble in water, easy to absorb moisture. The colour gradually deepens with the increase of impurity content, and crude morphine is a coffee-like brown powder. Under the same quality, the effect of injecting morphine is 10-20 times stronger than that of smoking opium.
Morphine, commonly used as its hydrochloride or sulfate, is an opioid alkaloid and an opioid receptor agonist. Pharmacological action: by mimicking the action of endogenous antinociceptive substances enkephalins, agonising central nervous opioid receptors and producing a powerful analgesic effect. It is effective for all pains, with stronger effects on persistent dull pain than intermittent sharp pain and visceral colic.
Symptoms of morphine use include: sweating, trembling, fever, high blood pressure, muscle pain and contractures. The side effects of morphine on the nerve centre are drowsiness and personality changes, causing a certain degree of comfort and euphoria; in the cerebral cortex, it can cause a decline in attention, thinking and memory performance, and long-term use of large doses of morphine can lead to symptoms of insanity, death and hallucinations; in the respiratory system, a large dose of morphine can lead to respiratory arrest and death. The highly addictive nature of morphine makes long-term users become seriously dependent on morphine, both physically and psychologically, resulting in a serious drug addiction, which causes morphine addicts to keep increasing the dosage in order to receive the same effect.
Morphine is absorbed from the gastrointestinal tract after oral administration, and is excreted mainly through the kidneys by the urine, with a small amount excreted through bile and breast milk; the morphine prototype accounts for 2-12%, and most of it (60-80%) is morphine-glucoside. Clearance half-life of ordinary tablets is 1.7-3 hours, extended-release tablets and controlled-release tablets its time to peak effect is longer, 2-3 hours, peak concentration is lower, reach steady state blood concentration fluctuation is small, clearance half-life is 3.5-5 hours.
Common detection methods for morphine in urine are chemical reaction, immunoassay, thin layer chromatography, high performance liquid chromatography, gas chromatography, high performance capillary electrophoresis, gas chromatography-mass spectrometry and molecular imprinting-chemiluminescence. These methods can be used for qualitative and quantitative detection of morphine in urine, and can also be used as an effective means for the diagnosis of morphine-dependent patients and the evaluation of detoxification efficacy. However, except for the immunoassay method, the other methods are basically limited by instruments and cannot achieve timely detection on site. The colloidal gold method of immunoassay is a good solution to this problem, which has been widely used.
【Precautions】
1、this test card is only used for one-time in vitro diagnosis, the same test card shall not be reused.
2、this product is used for qualitative detection of drugs or their metabolites, only for the judicial and public security system for drug users of the initial screening test, not for family testing, not for clinical diagnosis or treatment, medical institutions, workplaces for human urine sample testing.
3、This product is suitable for testing human urine samples.
4,、a large number of specimens for the test, please make a good mark, so as to avoid confusion.
5,、the experimental environment should be protected from the wind, avoiding too high temperature, too high humidity or too dry environment for the experiment.
6、each urine sample should use a new collection container and pipette to avoid contamination.
7、Do not freeze or use after the expiration date.
8、Do not use if the inner package is damaged.
